The prevalence of Rotavirus (RV)-related gastroenteritis in Cameroon was monitored in this study, identifying the circulating G-P types, and the presence of co-infection with intestinal parasites. The stool samples were examined for rotaviruses using chromatographic and molecular techniques, and parasites were identified by macroscopic and microscopic examination. 38% of samples were RV positive. Data revealed the presence of three different G-genotypes (G1, G2 and G8) and three Pgenotypes (P [8], P[6] and P[4]). The main G-P combination was G1+G2P[8]. Entamoeba histolytica was identified in 44.4% of stool samples. The G2P[8] genotype identified is an unusual strain with the G1P[8] or G2P[4] more common. Genotype G8 strains, also associated with animals, have been sporadically recovered from humans and have been considered for inclusion in bovine-human reassortant vaccine. Epidemiological RV strain surveillance should be continued in order to support RV vaccination campaigns. The results also show a high prevalence of intestinal parasite infections.
Evaluation of rotavirus and intestinal parasite infection in a paediatric population in West Cameroon: clinical characteristics and virus genotyping
DE DONNO, Maria Antonella;IDOLO, ADELE;GRASSI, Tiziana;
2013-01-01
Abstract
The prevalence of Rotavirus (RV)-related gastroenteritis in Cameroon was monitored in this study, identifying the circulating G-P types, and the presence of co-infection with intestinal parasites. The stool samples were examined for rotaviruses using chromatographic and molecular techniques, and parasites were identified by macroscopic and microscopic examination. 38% of samples were RV positive. Data revealed the presence of three different G-genotypes (G1, G2 and G8) and three Pgenotypes (P [8], P[6] and P[4]). The main G-P combination was G1+G2P[8]. Entamoeba histolytica was identified in 44.4% of stool samples. The G2P[8] genotype identified is an unusual strain with the G1P[8] or G2P[4] more common. Genotype G8 strains, also associated with animals, have been sporadically recovered from humans and have been considered for inclusion in bovine-human reassortant vaccine. Epidemiological RV strain surveillance should be continued in order to support RV vaccination campaigns. The results also show a high prevalence of intestinal parasite infections.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
