Intensive use of antibiotics induced adaptations in bacteria, which developed antibiotic resistance. This is becoming a serious health problem, particularly in the hospital, food industry, or public transport. It is also important to produce surfaces that not only are bactericidal but also prevent adhesion and the consequent biofilm formation, which can make the bacteria resistant to conventional disinfection methods. In this work, a simple and inexpensive method to obtain surfaces TiO2 film coated has been realized to prevent attachment and bacterial proliferation on surfaces. The synthesis and deposition procedure has been finalized to the realization of a uniform coating, whose physical, morphological, and structural features are suitable to inhibit the proliferation of the bacteria and in particular the adhesion of the biofilm. The suitability of the obtained coating has been attested by RBS, X-ray diffraction (XRD), SEM, UV-vis, and Raman techniques. The obtained coatings were homogeneous anatase titania films with an excellent adherence to the substrate and a transmittivity higher than 80% in the visible region. The results show that the TiO2 films considerably reduce microbial contamination on the surface (~98% reduction) feature that makes this coating suitable for antibacterial applications.
TiO2 films by sol-gel spin-coating deposition with microbial antiadhesion properties
Scrimieri L.
;Serra A.;Manno D.;Alifano P.;Tredici S. M.;Calcagnile M.;Calcagnile L.
2019-01-01
Abstract
Intensive use of antibiotics induced adaptations in bacteria, which developed antibiotic resistance. This is becoming a serious health problem, particularly in the hospital, food industry, or public transport. It is also important to produce surfaces that not only are bactericidal but also prevent adhesion and the consequent biofilm formation, which can make the bacteria resistant to conventional disinfection methods. In this work, a simple and inexpensive method to obtain surfaces TiO2 film coated has been realized to prevent attachment and bacterial proliferation on surfaces. The synthesis and deposition procedure has been finalized to the realization of a uniform coating, whose physical, morphological, and structural features are suitable to inhibit the proliferation of the bacteria and in particular the adhesion of the biofilm. The suitability of the obtained coating has been attested by RBS, X-ray diffraction (XRD), SEM, UV-vis, and Raman techniques. The obtained coatings were homogeneous anatase titania films with an excellent adherence to the substrate and a transmittivity higher than 80% in the visible region. The results show that the TiO2 films considerably reduce microbial contamination on the surface (~98% reduction) feature that makes this coating suitable for antibacterial applications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
