Risk of developing cancer increases with age, so are cognitive impairment disorders. That`s why it is hard to distinguish between cognitive changes related to cancer therapy and cognitive dysfunction caused by age or/and degenerative cognitive disorders. Chemo brain or chemo fog is known as a phenomenon that involves a lot of changes in cognitive functioning, mainly at the level of memory, attention and thinking. Often, patients report memory lapses, slower thinking and processing, attention focusing and distraction, thinking and behavioural disorganization, learning new skills or multi-tasking troubles. A lot of factors are supposed to be responsible for this changes like cancer itself, cancer treatment as chemotherapy, radiation therapy, hormones, surgery and psychological response to cancer. This study represents a sub-evaluation of the Italian group belonging to the European Cooperation in Science and Technology (COST) between 2011 and 2017 and prolonged with a new developed research protocol linked to cognitive impairment, nutrition and olfactory impairment. The Italian work has overcome both in a general way subjects with mild and strong cognitive impairments, admitted to clinics and hospitals, and a subgroup oncological geriatric patients with dementia due to oncological therapy. Geriatric oncological patients were investigated through to different typology: chemotherapy and immunotherapy for solid tumour. In particular, will be described the results of TD1005, administered to fifty patients (mean ag=e 75, 71; s.d. =4, 49) affected by oncological pathologies, recruited from the Oncology Unite Vito Fazzi Hospital Lecce (Italy). The results of this study show that cancer patients, despite cognitive impairment, express a nociceptive perception at a body level. This expression can be related to olfactory aspects and to a variation in the diet. Specific requirements in pain therapy with patients following immunotherapy.
Pain and Cognitive Impairment in oncologic geriatric patients: a PAIC study linked to nutrition and olfactory impairment
Sara Invitto
;
2019-01-01
Abstract
Risk of developing cancer increases with age, so are cognitive impairment disorders. That`s why it is hard to distinguish between cognitive changes related to cancer therapy and cognitive dysfunction caused by age or/and degenerative cognitive disorders. Chemo brain or chemo fog is known as a phenomenon that involves a lot of changes in cognitive functioning, mainly at the level of memory, attention and thinking. Often, patients report memory lapses, slower thinking and processing, attention focusing and distraction, thinking and behavioural disorganization, learning new skills or multi-tasking troubles. A lot of factors are supposed to be responsible for this changes like cancer itself, cancer treatment as chemotherapy, radiation therapy, hormones, surgery and psychological response to cancer. This study represents a sub-evaluation of the Italian group belonging to the European Cooperation in Science and Technology (COST) between 2011 and 2017 and prolonged with a new developed research protocol linked to cognitive impairment, nutrition and olfactory impairment. The Italian work has overcome both in a general way subjects with mild and strong cognitive impairments, admitted to clinics and hospitals, and a subgroup oncological geriatric patients with dementia due to oncological therapy. Geriatric oncological patients were investigated through to different typology: chemotherapy and immunotherapy for solid tumour. In particular, will be described the results of TD1005, administered to fifty patients (mean ag=e 75, 71; s.d. =4, 49) affected by oncological pathologies, recruited from the Oncology Unite Vito Fazzi Hospital Lecce (Italy). The results of this study show that cancer patients, despite cognitive impairment, express a nociceptive perception at a body level. This expression can be related to olfactory aspects and to a variation in the diet. Specific requirements in pain therapy with patients following immunotherapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
